JPH0323551B2 - - Google Patents
Info
- Publication number
- JPH0323551B2 JPH0323551B2 JP56165543A JP16554381A JPH0323551B2 JP H0323551 B2 JPH0323551 B2 JP H0323551B2 JP 56165543 A JP56165543 A JP 56165543A JP 16554381 A JP16554381 A JP 16554381A JP H0323551 B2 JPH0323551 B2 JP H0323551B2
- Authority
- JP
- Japan
- Prior art keywords
- general formula
- optically active
- carried out
- hexahydroindoquinolidinium
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU802525A HU183234B (en) | 1980-10-17 | 1980-10-17 | Process for the enantioselective synthesis of optically active cys-14-oxo-e-homo-eburnan |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57145876A JPS57145876A (en) | 1982-09-09 |
JPH0323551B2 true JPH0323551B2 (en]) | 1991-03-29 |
Family
ID=10959834
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56165543A Granted JPS57145876A (en) | 1980-10-17 | 1981-10-16 | Enantioselective synthesis of optically active 14-oxo-e-homo-eburnane derivative |
Country Status (5)
Country | Link |
---|---|
US (1) | US4399069A (en]) |
EP (1) | EP0050492B1 (en]) |
JP (1) | JPS57145876A (en]) |
DE (1) | DE3165576D1 (en]) |
HU (1) | HU183234B (en]) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX150317A (es) * | 1978-11-17 | 1984-04-16 | Unilever Nv | Mejoras en bolsa cerrada de material en hoja para detergentes en particulas |
US5122607A (en) * | 1989-06-21 | 1992-06-16 | Richter Gedeon Vegyesczeti Gyar Rt. | Racemic and optically active octahydro-indolo(2,3-a) tetrahydropyranyl (2,3-c) quinolizine diester derivatives and process for preparing the same |
JP4776843B2 (ja) | 1999-10-01 | 2011-09-21 | イムノゲン インコーポレーティッド | 免疫複合体及び化学療法剤を用いる癌治療用組成物及び方法 |
US11083714B2 (en) | 2018-03-31 | 2021-08-10 | Molecular International Research, Inc. | Selective anti-cancer agent effective for prevention and treatment |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3770724A (en) * | 1970-03-31 | 1973-11-06 | Roussel Uclaf | Process for preparing pentacyclic alkaloids |
AU499923B2 (en) * | 1975-06-27 | 1979-05-03 | Richter Gedeon Vegyeszeti Gyar N | Indoloquinolizine derivatives & their production |
GB2010833B (en) * | 1977-11-25 | 1982-04-15 | Scras | Homoerburnamine preparation |
FR2445328A1 (fr) * | 1978-07-12 | 1980-07-25 | Richter Gedeon Vegyeszet | Derives du 14-oxo-e-homo-eburnane, leur procede de preparation et leur utilisation comme medicament |
HU178402B (en) * | 1978-08-01 | 1982-04-28 | Richter Gedeon Vegyeszet | New process for producing okrahydro-indolo-square bracket-2,3-a-square bracket closed-quinolysines |
HU181495B (en) * | 1979-05-31 | 1983-07-28 | Richter Gedeon Vegyeszet | Process for producing hydroxy-imino-eburnane derivatives |
-
1980
- 1980-10-17 HU HU802525A patent/HU183234B/hu not_active IP Right Cessation
-
1981
- 1981-10-16 JP JP56165543A patent/JPS57145876A/ja active Granted
- 1981-10-16 DE DE8181304833T patent/DE3165576D1/de not_active Expired
- 1981-10-16 US US06/312,128 patent/US4399069A/en not_active Expired - Fee Related
- 1981-10-16 EP EP81304833A patent/EP0050492B1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE3165576D1 (en) | 1984-09-20 |
EP0050492B1 (en) | 1984-08-15 |
EP0050492A1 (en) | 1982-04-28 |
JPS57145876A (en) | 1982-09-09 |
HU183234B (en) | 1984-04-28 |
US4399069A (en) | 1983-08-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP2003513974A (ja) | イミダゾリジノン系αv−インテグリン拮抗薬の製造方法および製造用中間体 | |
HU180905B (en) | Process for preparing vincadifformine | |
JPS5827276B2 (ja) | ビンカミンおよびその関連化合物の製法 | |
CN115010644A (zh) | 一种2,3-二取代吲哚啉类化合物的制备方法 | |
US4283401A (en) | Process for the preparation of 11-bromo-vincaminic acid ester derivatives and their use in protecting animals against cerebral hypoxy | |
Li et al. | Enantioselective Intramolecular Desymmetric α‐Addition of Cyclohexanone to Propiolamide Catalyzed by Sodium L‐Prolinate | |
US4316029A (en) | Synthesis of vincaminic acid derivatives | |
JPH05112525A (ja) | 4−ヒドロキシ−2−オキソ−ピロリジン−1−イル−アセトアミドの製造方法 | |
JPH0323551B2 (en]) | ||
JPH0714932B2 (ja) | ヒドロキシイミノオクタヒドロインドール(2,3−a)キノリジン誘導体の製造方法 | |
JPH064556B2 (ja) | シクロヘキサンジオン誘導体の製法 | |
GB2036744A (en) | Eburnane derivatives | |
JPH0543703B2 (en]) | ||
US4400514A (en) | Process for the preparation of apovincaminic acid ester derivatives | |
JPS6148839B2 (en]) | ||
JPH1087633A (ja) | キラルなコハク酸誘導体の製造方法 | |
JPH0227994B2 (en]) | ||
EP0058071A2 (en) | Process and intermediates for preparing pirbuterol | |
JP3017338B2 (ja) | インドールアルカロイド誘導体製造用の新規中間体化合物 | |
RU2056423C1 (ru) | СПОСОБ ПОЛУЧЕНИЯ (-)- 1β -ЭТИЛ- 1α -(ГИДРОКСИМЕТИЛ)-1,2,3,4,6,7,12, 12В 1α -ОКТАГИДРОИНДОЛ(2,3-А)ХИНОЛИЗИНА (ВАРИАНТЫ), 1-ЭТИЛ-1(ГИДРОКСИМЕТИЛ)-1,2,3,4,6,7-ГЕКСАГИДРО-12Н-ИНДОЛ(2,3-А)ХИНОЛИЗИН И ЕГО ОПТИЧЕСКИ АКТИВНЫЕ СОЛИ | |
KR100574435B1 (ko) | 후퍼진 b 유도체와 이의 제조방법 | |
BE1004471A3 (fr) | Nouveaux derives diester d'octahydro-indolo-[2,3-a]-tetrahydropyranyl [2,3-c] quinolizine racemiques et optiquement actifs et procede pour les preparer. | |
JPH05320168A (ja) | 光学活性ラクトン化合物の製造方法 | |
US3578670A (en) | Nicotinamide intermediates and process for preparing same | |
GB2105718A (en) | Process for the preparation of alkoxyvincaminic acid esters and alkoxyapovincaminic acid esters |